A system for inactivation of pathogens on a surface may include a first light source that emits first light having a peak wavelength in a range of 100 nm to 500 nm; a second light source that emits second light that is visible light; control electronics configured to control a first power state of the first light source and a second power state of the second light source. The first power state and the second power state may be independently controlled. The system may be configured such that an illumination area of the first light and the second light is limited to the inactivation area.