OLAF PETERS,NICO BRAEUER,INA THIEME,KATJA PRELLE,HANS-PETER MUHN,KARL-HEINRICH FRITZEMEIER
申请号：
BRPI0814207
公开号：
BRPI0814207A2
申请日:
2008.07.11
申请国别(地区):
BR
年份:
2015
代理人:
摘要：
The invention refers to 8²-substituted estra-1,3,5(10)-triene derivatives of general formula I their use as pharmaceutical active ingredients, which have in vitro a higher affinity to estrogen receptor preparations from rat prostates than to estrogen receptor preparations from rat uteri and in vivo a preferential action in the ovary in comparison to the uterus, their production, their therapeutic use and pharmaceutical dispensing forms that contain the new compounds.
