PROBLEM TO BE SOLVED: To provide novel medicaments which are useful as cytoprotective medicaments, in particular as neuroprotective, cardioprotective and/or hepatoprotective medicaments which can inhibit and/or treat cell death necrosis and/or pathological apoptosis and/or necroptosis, can stop cell degeneration, in particular nerve cell degeneration, and can effectively protect cells from degenerative phenomenons.SOLUTION: A chemical compound represented by the following formula is included in representatives of novel cholest-4-en-3-one oxime derivatives.【課題】細胞死のネクローシス及び／又は病理学的アポトーシス及び／又はネクロトーシスを阻止し及び／又は処置することができ、細胞変性、特に神経細胞変性を止め、細胞を変性現象から有効に保護できる細胞保護薬、特に、神経保護薬、心保護薬及び／又は肝保護薬として有用な新規医薬の提供。【解決手段】下式で表される化合物を代表例とする新規コレスト－４－エン－３－オンオキシム誘導体。【選択図】なし
