Use of a phthalide for the manufacture of a medicament is provided. The medicament is particularly for treating and/or delaying the degeneration of Purkinje cells, and the phthalide is selected from the group consisting of n-butylidenephthalide (BP), a metabolic precursor of BP, a pharmaceutically acceptable salt of a metabolic precursor of BP, a pharmaceutically acceptable ester of a metabolic precursor of BP, and combinations thereof.一種使用苯酞化合物(phthalide)於製備藥劑的用途，該藥劑特別係用以治療及/或延緩浦肯野细胞(Purkinje cells)退化，且該苯酞化合物係選自以下群組：亞丁基苯酞、亞丁基苯酞之代謝前驅物、亞丁基苯酞之代謝前驅物之醫藥可接受鹽、亞丁基苯酞之代謝前驅物之醫藥可接受酯、以及前述之組合。
