Robert Gerald Whalen,Clayton W. Beard,Li Xu,Hakima Sbai
申请号:
US14207135
公开号:
US09353158B2
申请日:
2014.03.12
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This document provides methods and materials for producing immune responses against hepatitis B viruses. For example, polypeptides, nucleic acid molecules encoding such polypeptides, virus-like particles containing such polypeptides, vaccine preparations containing one or more polypeptides provided herein, vaccine preparations containing one or more nucleic acid molecules provided herein, vaccine preparations containing one or more virus-like particles provided herein, and methods for inducing immune responses against hepatitis B viruses within mammals (e.g., humans) are provided.