THE UNITED STATES OF AMERICA; AS REPRESENTED BY THE SECRETARY; DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
CHANG, GWONG-JEN J.,DAVIS, BRENT S.
申请号：
CA3026807
公开号：
CA3026807A1
申请日:
2017.06.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Transcriptional units encoding Zika virus (ZIKV) premembrane (prM) and envelope (E) proteins, which upon translation form Zika virus-like particles (VLPs), are described. Use of the transcriptional units and VLPs in three different ZIKV vaccine platforms is described. Immunoassay- based detection methods using ZIKV VLPs are described for the diagnosis of ZIKV infection.
