The U.S.A.; as represented by the Secretary; Department of Health and Human Services
发明人:
Gwong-Jen J. Chang,Brent S. Davis
申请号：
US16309288
公开号：
US20190309025A1
申请日:
2017.06.09
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Transcriptional units encoding Zika virus (ZIKV) premembrane (prM) and envelope (E) proteins, which upon translation form Zika virus-like particles (VLPs), are described. Use of the transcriptional units and VLPs in three different ZIKV vaccine platforms is described. Immunoassay-based detection methods using ZIKV VLPs are described for the diagnosis of ZIKV infection.
