BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA MBH
发明人:
POHL, JENS,PLOGER, FRANK,KRUSE, MICHAEL
申请号：
CA2627370
公开号：
CA2627370C
申请日:
2006.11.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The application relates to novel biosynthetic growth factor mutants, derivedfrom GDF-5, which exhibit improved biological activity. Mutations at positions453 and 456 of human GDF-5 are disclosed, as well as use of these mutants intherapy of diseases associated with tissue degeneration/destruction.
