High activity growth factor mutants

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专利权人:

Jens Pohl;Michael Kruse;Frank Ploeger

发明人:

Jens Pohl,Frank Ploeger,Michael Kruse

申请号：

US12094227

公开号：

US08188226B2

申请日:

2006.11.17

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The application relates to novel biosynthetic growth factor mutants, derived from GDF-5, which exhibit improved biological activity. Mutations at positions 453 and 456 of human GDF-5 are disclosed, as well as use of these mutants in therapy of diseases associated with tissue degeneration/destruction.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/