The present invention relates to a kind of compound, it is used to inhibit from columnar cell, and the secretion of the thymic stromal lymphopoietin (TSLP) used. It has been confirmed that the compound of the present invention significantly inhibits the secretion of the TSLP from columnar cell, therefore compound is used as a candidate material of the treatment and prevention of atopic dermatitis, allergic dermatitis and/or inflammatory bowel disease.
