Hong Ryeol Jeon,Do-Woo Kwon,Bong-Sang Lee,Su-Jun Park,Jiyeong Han,Myeongcheol Kil,Min Seop Kim
申请号：
US15320446
公开号：
US10045993B2
申请日:
2015.06.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical preparation comprising entecavir as an active ingredient, wherein an antioxidizing agent is added to enhance stability of entecavir, and a method for preparing the same. According to the present invention, the invention has an effect that entecavir can be stably maintained in a pharmaceutical preparation containing a certain amount or more of moisture by adding the antioxidizing agent, thereby a pharmaceutical preparation can be provided as a formulation containing a certain amount or more of moisture, for example, an orally disintegrating film formulation.
