Inhibiteurs de la cystéine protéase

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专利权人:

Medivir UK Ltd

发明人:

申请号：

EP14162956.8

公开号：

EP2752404A1

申请日:

2011.06.16

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

There is provided a process for the preparation of a compound of formula III, comprising the step of oxidising the compound of formula 2b wherein n is 2； R2a and R2b are independently H or F； R3 is 1-methylcyclopentylmethyl or 1-fluorocyclopentylmethyl； R3' is CH3 or F； R4 is C1-C6alkyl, C1-C6haloalkyl or C3-C6cycloalkyl, wherein C3-C6cycloalkyl is optionally substituted with methyl, CF3 or one or two fluoro. Compounds and processes used in the preparation of a compound of formula III are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/