KIM, Chanhyuk,YOUNG, Travis,CAO, Yu,MA, Jennifer,KIM, Minsoo,PINKERTON, Stephanie,SCHULTZ, Peter
申请号：
ES14853242
公开号：
ES2741308T3
申请日:
2014.10.15
申请国别(地区):
ES
年份:
2020
代理人:
摘要：
Disclosed herein are switches for regulating the activity of a chimeric antigen receptor effector cells (CAR-ECs). The switches generally comprise a chimeric antigen receptor-interacting domain (CAR-ID) and a target interacting domain (TID). The switch may further comprise a linker. Further disclosed herein are methods of using the switches for the treatment of one or more conditions or diseases in a subject in need thereof.
