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CHIMERIC ANTIGEN RECEPTOR T CELL SWITCHES AND USES THEREOF
专利权人:
The California Institute for Biomedical Research
发明人:
KIM, Chanhyuk,YOUNG, Travis,CAO, Yu,MA, Jennifer,KIM, Minsoo,PINKERTON, Stephanie,SCHULTZ, Peter, G.
申请号:
EP14853242
公开号:
EP3057991A4
申请日:
2014.10.15
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Disclosed herein are switches for regulating the activity of a chimeric antigen receptor effector cells (CAR-ECs). The switches generally comprise a chimeric antigen receptor-interacting domain (CAR-ID) and a target interacting domain (TID). The switch may further comprise a linker. Further disclosed herein are methods of using the switches for the treatment of one or more conditions or diseases in a subject in need thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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