The invention concerns a method for an aseptic assembly of a multi-component medical device (60) comprising the steps of:- providing a first component (12) of the medical device (60) in a first container (10) and a second component (40) of the medical device (60) in a second container (38), wherein each of the separated containers (10,38) comprises a ruptureable portion (28,52),- sterilizing the first component (12) in the first container (10) using a first sterilization technique and sterilizing the second component (40) in the second container (38) using a second sterilization technique,- joining the first and second container (10,38) while arranging the ruptureable portions (28,52) in an overlapping configuration which is aseptically sealed against the surroundings,- transferring one of the components through the ruptureable portions (28,52) and aseptically assembling the components to form the medical device (60) as a sterile package.