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ГЕТЕРОАРИЛМЕТИЛАМИДЫ
专利权人:
Ф. ХОФФМАНН-ЛЯ РОШ АГ (CH)
发明人:
ХЕБАЙЗЕН Пауль (CH),ЦОФФМАНН ЕНЗЕН Заннах (CH),МАТИЛЬ Юг (CH),РЁФЕР Штефан (CH),РАЙТ Мэттью (CH)
申请号:
RU2013113118/04
公开号:
RU2013113118A
申请日:
2011.09.06
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. Compounds of the formula wherein A, Au and A are selected from N or CH with the proviso that at least one of A, A or A is N and at least one of A, A or A is CH, R is selected from the group consisting of lower alkyl, cycloalkyl, lower cycloalkylalkyl, lower hydroxyalkyl, lower alkoxyalkyl, lower haloalkyl, lower carbamoylalkyl, lower alkylcarbonylaminoalkyl, lower phenylalkyl, lower heterocyclylalkyl wherein the heterocyclyl group is unsubstituted or substituted by an oxo group, a lower heteroarylalkyl, the unsubstituted or unsubstituted or unsubstituted lower alkyl, and phenyl which is unsubstituted or mono- or disubstituted by halogen R and R are independently of one another hydrogen or halogen R and R are independently selected from the group consisting of hydrogen, lower alkyl, lower alkoxy, halogen, lower haloalkoxy, lower haloalkoxy and cyano R is selected from the group consisting of hydrogen, lower alkoxy, halogen, lower haloalkyl, lower haloalkoxy and cyano or R and R together with the C atoms to which they are attached form a five- or six-membered carbocycle or five- or a six-membered heterocycle containing one, two or three heteroatoms selected from the group consisting of N, O and S, said carbocycle or heterocycle being unsubstituted or substituted by one or two substituents independently selected from the group consisting of lower alkyl, lower alkoxy, halogen, lower haloalkyl, lower haloalkoxy and cyano r and independently from each other represent hydrogen or lower alkyl R is a five- or six-membered heteroaryl group, containing or halogen, lower haloalkyl, lower haloalkoxy and cyano, or R and R together with the C atoms to which they are attached form a five- or six-membered carbocycle or a five- or six-membered heterocycle containing one, two or three heteroatoms, selected from the group consisting of N, O and S, said carbocycle or heterocycle being unsubstituted or substituted by one or two substituents independently selected from the group consis
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