Wulf Paschen,Wei Yang,Huaxin Sheng,David S. Warner
申请号:
US13641639
公开号:
US20130046010A1
申请日:
2011.04.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed herein are methods relating to inhibiting or reducing proliferation of a cancer cell, for treating cancer in a subject in need of treatment, predicting the risk of progression of cancer to a more aggressive cancer, and screening for cancer in a subject, that comprise detecting and/or decreasing the levels of SUMO conjugated proteins and detecting and/or interfering with SUMO conjugation.