Sanjeev H. SATYAL,Satyajit Sujit Kumar Mitra,Austin L. Gurney
申请号:
US14842398
公开号:
US20160082079A1
申请日:
2015.09.01
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to compositions comprising Wnt antagonists and methods of treating Wnt-associated diseases and disorders, such as cancer, inducing differentiation, and reducing the frequency of cancer stem cells, as well as novel methods of screening for such Wnt antagonists. In particular, the invention discloses soluble FZD, SFRP and Ror receptors and their use.