Adoptive cell therapy with young T cells

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专利权人:

发明人:

Mark E. Dudley,Steven A. Rosenberg

申请号：

US13742541

公开号：

US09074185B2

申请日:

2013.01.16

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The invention provides a method of promoting regression of a cancer in a mammal comprising (i) culturing autologous T cells (ii) expanding the cultured T cells (iii) administering to the mammal nonmyeloablative lymphodepleting chemotherapy and (iv) after administering nonmyeloablative lymphodepleting chemotherapy, administering to the mammal the expanded T cells, wherein the T cells administered to the mammal are about 19 to about 35 days old and have not been screened for specific tumor reactivity, whereupon the regression of the cancer in the mammal is promoted.

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中国工程科技知识中心

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