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DERIVES D'ANTHRANYLE AYANT UNE ACTIVITE ANTICHOLECYSTOKININE (ANTI-CCK-1), LEUR PROCEDE DE PREPARATION ET LEUR UTILISATION PHARMACEUTIQUE
专利权人:
ROTTAPHARM S.P.A.
发明人:
MAKOVEC, FRANCESCO,VARNAVAS, ANTONIO,LASSIANI, LUCIA,ROVATI, LUCIO CLAUDIO
申请号:
CA2493789
公开号:
CA2493789C
申请日:
2003.07.23
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
Anthranylic compounds having anti-CCK activity of general formula (I) inwhich, n is a whole number lying between 0 and 7; R1 is chosen independentlyfrom the groups (II), in which X1 is chosen independently from, S, O, NR2 andX2 is a group chosen from: H, C1-C4 alkyl, F, Cl, CF3, OCH3, OC2H5, CN; R2 ischosen from H or CH3; R3 is chosen from H, CH3, F, Cl, CF3, OCH3; R4 is chosenfrom the groups: H, -S-(CH2)m-R5, -SO2- (CH2)m-R5 (n different from 0), abranched alkyl group, a cyclo alkyl, a cyclo alkenyl, the group 1 or 2adamantile, a phenyl group optionally substituted; R5 is chosen from thegroups: H, linear or branched alkyl, cyclo alkyl, the group 1 or 2 adamantile,a suitably substituted phenyl group.
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来源网址:
http://www.ckcest.cn/home/

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