PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for treating allergic rhinitis, pollinosis, and central nervous system disease which have high therapeutic effect and can be supplied stably, and to provide production methods thereof.SOLUTION: The invention provides a pharmaceutical composition for treating at least either one of allergic rhinitis and pollinosis containing an immortalization stem cell-culture supernatant containing a secretory component from immortalization stem cells obtained by culturing the immortalization stem cells which have been immortalized, or their secretory component, the stem cells being either one of tooth-pulp stem cells or myeloid stem cells.SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】高い治療効果を有し、安定に供給することが可能な、アレルギー性鼻炎、花粉症及び中枢神経系疾患を治療するための医薬組成物及びその製造方法の提供。【解決手段】不死化された不死化幹細胞を培養することによって得られた、不死化幹細胞からの分泌成分を含む不死化幹細胞培養上清もしくはその分泌成分を含み、前記幹細胞が歯髄幹細胞又は骨髄幹細胞のいずれか一方である、アレルギー性鼻炎及び花粉症の少なくとも一方の治療のための医薬組成物。【選択図】なし
