PROBLEM TO BE SOLVED: To provide a pharmaceutical composition that expresses a sufficient and excellent penile erection function by administering a low dose of a PDE5 inhibitor having few side effects to the middle-aged and elderly suffering from ED (erectile dysfunction) and highly frequently taking anti-anginal agents and anti-hypertensive agents.SOLUTION: The pharmaceutical composition contains the PDE5 inhibitor and a crude drug having a sedative action, more specifically, the composition containing Valeriana fauriei, Uncaria rhynchophylla, Passiflora caerulea and Humulus luputus.COPYRIGHT: (C)2012,JPO&INPIT【課題】EDに悩む、狭心症薬や降圧薬の服用率が高い中高年に、副作用の少ない低用量でのPDE5阻害剤投与で、充分かつ優れた陰茎勃起機能を発現する医薬組成物を提供すること。【解決手段】PDE5阻害剤と、鎮静作用を有する生薬、より詳しくはカノコソウ、チョウトウコウ、トケイソウ又はホップを含有する医薬組成物。【選択図】なし