< Topic >The sense of taste aural masking, adjustment possibility of conservation of the active ingredient with especially acidic environment and emission characteristic, the mucus irritability effect and the poisonous aural masking of the active ingredient of a certain genus, it possesses the sense of taste which the mask is done, stabilizes, it proposes the new garenusu formulation system which at the same time makes the preparation of pH non dependant water form possible.SolutionsThis invention is hydrophobia completely, the water or the surface active agent or the emulsifier or the trace composition completely are not included, at least the hydrophobic wax of 1 genera and feature that at least the non neutralization fatty acid of 1 genera is included, garenusu formulation system of lipid solid-state form of particle is dealt with.【課題】味覚マスキング、特に酸性環境での有効成分の保護、放出特性の調整可能性、ある種の有効成分の粘液被刺激性効果及び毒性のマスキング、マスクした味覚を有し、安定し、かつpH非依存性の水性形状の調製を可能にする新規なガレヌス製剤系を提案する。【解決手段】本発明は、全く疎水性であり、水も、界面活性剤も、乳化剤も、微量の溶剤も全く含まず、少なくとも1種の疎水性蝋及び少なくとも1種の非中和脂肪酸を含むことを特徴とする、脂質固体粒子形状のガレヌス製剤系を対象とする。
