abstract the present invention provides antigen-binding molecules containing (i) an antigen-binding domain whose antigen-binding activity varies depending on ion concentration conditions, (ii) an fc? -binding domain having fc? riib-selective binding activity, and (iii) an fcrn-binding domain having fcrn-binding activity under an acidic ph range condition, and methods of decreasing plasma antigen concentration as compared to before administering the molecule, which include the step of administering the molecule . Abstract of the Patent Summary: "Antigen-binding molecule for promoting antigen disappearance via fc? riib". The present invention relates to antigen-binding molecules containing (i) an antigen-binding domain whose antigen-binding activity varies depending on ion concentration conditions, (ii) a fc? having fc? riib selective binding activity and (iii) an fcrn binding domain having fcrn binding activity under an acid ph range condition and methods of decreasing plasma antigen concentration as compared to prior to administration of the molecule which include the step of administering the molecule.abstract the present invention provides antigen-binding molecules containing (i) an antigen-binding domain whose antigen-binding activity varies depending on ion concentration conditions, (ii) an fc?-binding domain having fc? riib-selective binding activity, and (iii) an fcrn-binding domain having fcrn-binding activity under an acidic ph range condition, and methods of decreasing plasma antigen concentration as compared to before administering the molecule, which include the step of administering the molecule. tradução do resumo resumo patente de invenção: "molécula de ligação a antígeno para promoção de desaparecimento de antígeno através de fc?riib". a presente invenção refere-se a moléculas de ligação a antígeno contendo (i) um domínio de ligação a antígeno cuja atividade de ligação a antígeno varia dependendo das condições de concentração de íons, (ii) um domínio
