CYSTEAMINE IN THE TREATMENT OF FIBROTIC DISEASE

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专利权人:

SEATTLE CHILDRENS RESEARCH INSTITUTE

发明人:

EDDY ALLISON A.,OKAMURA DARYL M.

申请号：

IN3049DEN2014

公开号：

IN3049DEN2014A

申请日:

2014.04.11

申请国别(地区):

IN

年份:

2015

代理人:

摘要：

Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we describe the reduction of extracellular matrix (ECM) deposition interstitial fibroblasts interstitial volume expression of Collagen I mRNA and protein expression of profibrotic cytokines and macrophage infiltration by Cysteamine treatment.

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