SEATTLE CHILDRENS RESEARCH INSTITUTE;SEATTLE CHILDREN'S RESEARCH INSTITUTE
发明人:
EDDY, ALLISON A.,OKAMURA, DARYL M.
申请号:
CA2853484
公开号:
CA2853484A1
申请日:
2011.10.26
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
Fibrotic diseases are characterized by the replacement of healthy tissue with scar tissue and extracellular matrix in response to tissue damage. Here we describe the reduction of extracellular matrix (ECM) deposition, interstitial fibroblasts, interstitial volume, expression of Collagen I mRNA and protein, expression of profibrotic cytokines and macrophage infiltration by Cysteamine treatment.