NI Chiyou,NI Chiyou,PARK Minnie,PARK Minnie,SHAO Bin,SHAO Bin,TAFESSE Laykea,TAFESSE Laykea,YAO Jiangchao,YAO Jiangchao,YOUNGMAN Mark,YOUNGMAN Mark
申请号：
SI201231060
公开号：
SI2753606T1
申请日:
2012.08.31
申请国别(地区):
SI
年份:
2017
代理人:
摘要：
The present disclosure provides substituted pyrimidine compounds of Formula (I), and the pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A1, X, A2, W1, W2, E, Z, and R4 are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of sodium channels. Compounds of the present disclosure are especially useful for treating pain.
