C13 Metabolic biomarkers for non-alcoholic fatty liver disease using in vivo magnetic resonance spectroscopy of hyperpolarized 1-13C pyruvate

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专利权人:

전남대학교산학협력단

发明人:

정광우,김윤현,문충만

申请号：

KR1020170035451

公开号：

KR1019394540000B1

申请日:

2017.21.03

申请国别(地区):

KR

年份:

2019

代理人:

摘要：

The present invention relates to a method of providing information for nonalcoholic fatty liver disease (NAFLD) diagnosis using a magnetic resonance spectroscopy image of hyperpolarized [1-13C] pyruvate C13 and, more specifically, to a method of providing a quantitative biomarker for nonalcoholic fatty liver disease diagnosis by measuring quantitative changes of various cell metabolites for 0 week, 2 weeks, 4 weeks, and 6 weeks during a diet period for an animal model of a nonalcoholic fatty liver disease derived by high-fat diet (HFD) consumption in real time at intervals of second units.

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中国工程科技知识中心

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http://www.ckcest.cn/home/