This invention recognizes the pancreas cancer cell or organization uniquely, and regards nuclear acid aputama and its use which can be connected. Nuclear acid aputama which relates to this invention does not connect to normal pancreas organization, connects to only the pancreas cancer cell or organization uniquely, is used for the usefulness pancreas cancer diagnosis and remedy as a composition. Furthermore, not only CaPan 1 which is latter-term pancreas cancer cell stocks, because it can detect also Panc 1 which is early pancreas cancer cell stocks, early be able to utilize, although survival ratio of the pancreas cancer patient is raised, it can contribute to pancreas cancer diagnosis nuclear acid aputama which relates to this invention.本発明は膵臓癌細胞または組織を特異的に認識し、そして結合できる核酸アプタマー及びその用途に関する。本発明に係る核酸アプタマーは、正常すい臓組織には結合せず、膵臓癌細胞または組織にのみ特異的に結合して、膵臓癌診断及び治療用組成物として有用に用いられる。さらに、本発明に係る核酸アプタマーは、後期膵臓癌細胞株であるCaPan-1だけでなく、初期膵臓癌細胞株であるPanc-1も検出できるため、早期膵臓癌診断に利用でき、膵臓癌患者の生存率を高めるのに寄与できる。
