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Pancreatic cancer therapy with a parvovirus
专利权人:
DEUTSCHES KREBSFORSCHUNGSZENTRUM;RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
发明人:
ROMMELAERE, JEAN,RAYKOV, ZAHARI,SCHLEHOFER, JOERG,KIPRIJANOVA, IRINA,HEIMBERGER, TANJA,ANGELOVA, ASSIA,GELETNEKY, KARSTEN,APRAHAMIAN, MARC
申请号:
DK11003657
公开号:
DK2431045T3
申请日:
2008.12.23
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
Described is a pharmaceutical composition containing (a) a parvovirus and (b) a chemotherapeutic agent, preferably as separate entities. The parvovirus might be based on parvovirus H1, LuIII, Mouse minute virus (MMV), Mouse parvovirus (MPV), Rat minute virus (RMV), Rat parvovirus (RPV), Rat virus (RV), vectors based on the foregoing viral species, and/or cells capable of actively producing the foregoing viral species. The pharmaceutical composition is beneficial for the treatment of a tumor. Tumors for which a parvovirus or the adjunction of the invention has particular utility include glioma, medulloblastoma, meningioma and pancreatic cancer. Preferred chemotherapeutic agents are gemcitabine and Temozolodine.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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