The invention provides a compartmentalised gel matrix comprising one or more compartments, wherein each compartment comprises a volume of hydrophobic medium and one or more aqueous droplets therein. The invention further provides a pharmaceutical formulation comprising a compartmentalised gel matrix according to the invention, a synthetic cell comprising a compartmentalised gel matrix according to the invention and a synthetic tissue comprising a compartmentalised gel matrix according to the invention.L'invention concerne une matrice de gel compartimentée comprenant un ou plusieurs compartiments, chaque compartiment comprenant un volume de milieu hydrophobe et une ou plusieurs gouttelettes aqueuses en son sein. L'invention concerne en outre une formulation pharmaceutique comprenant la matrice de gel compartimentée selon l'invention, une cellule synthétique comprenant la matrice de gel compartimentée selon l'invention et un tissu synthétique comprenant la matrice de gel compartimentée selon l'invention.