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Aza-epoxy-Guiana derivatives and cancer treatment
专利权人:
The United States of America;The United States of America, as represented by The Secretary, Department of Health & Human Services;University of Hawaii; as represented by The Secretary; Department of Health & Human Services
发明人:
CHAIN, William J.,BEUTLER, John A.,FASH, David,FIGG, William D.,LI, Zhenwu,PEER, Cody John,RAMOS, Joe William,SULZMAIER, Florian J.
申请号:
ES15705869
公开号:
ES2682368T3
申请日:
2015.02.05
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
Compound of formula (I) or formula (II): ** Formula ** or an epimer thereof, where R1 is isopropyl or isopropylenyl, R2 and R3 are independently C1-C6 alkyl, R4 is C6-C10 aryl or cycloalkyl C3-C8, wherein aryl is optionally substituted with C1-C6 alkyl, hydroxyC1-C6 alkyl, C1-C6 alkoxy, halo or nitro, R5 is hydrogen or C1-C6 alkyl, and R6 is C1-C6 alkyl, hydroxyalkyl C1-C6 or fluoroalkyl C1-C6.Compuesto de fórmula (I) o fórmula (II):**Fórmula** o un epímero del mismo, en las que R1 es isopropilo o isopropilenilo, R2 y R3 son independientemente alquilo C1-C6, R4 es arilo C6-C10 o cicloalquilo C3-C8, en el que el arilo está opcionalmente sustituido con alquilo C1-C6, hidroxialquilo C1-C6, alcoxilo C1-C6, halo o nitro, R5 es hidrógeno o alquilo C1-C6, y R6 es alquilo C1-C6, hidroxialquilo C1-C6 o fluoroalquilo C1-C6.
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