The invention relates to a compound with general formula (III) or a salt thereofSolvates or prodrugs,Together with the medical uses they are involved in,A1 was selected from the following group,The group consisted of the following: N and C ￣ R8；A2 was selected from the following group,The group consisted of the following: N and C ￣ R3；A3 was selected from the next group,The group consisted of the following: N and C ￣ R9；A4 and A5 and A6 were independently selected from the following group,The group consisted of the following: N and C ￣ R1；R1 is selected from the lower group,The group consists of the following items: hydrogen(C1 ￣ C3) alkylHalogen(C1-C3) alkoxy and (C1-C3) alkyl halides；R2 was selected from the next group,The group consists of the following items: hydrogenHalogen and (C1 ￣ C3) alkyl；R3 was selected from the lower group,The group consists of the following items: hydrogen(C1 ￣ C3) alkylNR4R5、(C1-C3) alkyl-nr4r5 and cyano groups；R4 and R5 were independently selected from the lower group,The group consists of the following items: hydrogen(C3 ￣ C5) cycloalkane(C3 ￣ C5) heterocyclic alkyl(C1 ￣ C3) alkyl,Or R4 and R5 form 5-to 7-membered heterocycles with their attached nitrogen atoms,In addition to the nitrogen atom mentioned above,It also optionally includes another heteroatom group,The heteroatom group is selected from the following group,The group consists of the following: O and NR6,R6 was selected from the lower group,The group consists of the following items: hydrogenMethylAcetyl and formyl groups；Y is selected from the following group,The group consists of the following: O and S；R7 was selected from the following group,The group consists of the following items: hydrogenAnd (C1 ￣ C3) alkyl groups；R8 was selected from the following group,The group is composed of the following: (C1-C4) alkyl group(C3 ￣ C5) cycloalkaneAnd (C3-C5) heterocyclic alkyl group；R9 was selected from the following group,The group consists of the following items: hydrogen(C1 ￣ C3
