CARL H. JUNE,MICHAEL C. MILONE,BRUCE L. LEVINE,DAVID L. PORTER,MICHAEL D. KALOS
申请号:
PT17153799
公开号:
PT3214091T
申请日:
2011.12.09
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The present invention provides compositions and methods for treating cancer in a human. The invention includes relates to administering a genetically modified T cell to express a CAR wherein the CAR comprises an antigen binding domain, a transmembrane domain, a costimulatory signaling region, and a CD3 zeta signaling domain.