CO-CRYSTALS OF (S)-N-METHYL-8-(1-((2- METHYL-[4, 5- BIPYRIMIDIN]-6YL)AMINO)PROPAN-2-YL)QUINOLINE-4-CARBOXAMIDE AND DEUTERATED DERIVATIVES THEREOF AS DNA-PK INHIBITORS
NTI ADDAE KWAME WIREDU,O NEIL SIMON ADAM,ZHANG YUEGANG,WALDO MICHAEL,MUDUNURI PRAVEEN,SONG BIN,VAN ALSTEN JOHN GREGG,STROHMEIER MARK,STAVROPOULOS KATHY,KADIYALA IRINA NIKOLAEVNA,NAVAMAL METTACHIT
申请号：
IN201637014507
公开号：
IN201637014507A
申请日:
2016.04.26
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure: wherein each of R1 and R2 is H or 2H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.
