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CO-CRYSTALS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME
专利权人:
Vertex Pharmaceuticals Incorporated
发明人:
Kwame Wiredu Nti-Addae,Simon Adam O'Neil,Yuegang Zhang,Michael Waldo,Praveen Mudunuri,Bin Song,John Gregg Van Alsten,Mark Strohmeier,Kathy Stavropoulos,Irina Nikolaevna Kadiyala,Mettachit Navamal,Simon Adam ONeil
申请号:
US16038696
公开号:
US20180325897A1
申请日:
2018.07.18
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to compositions and co-crystals each comprising a compound of formula I having the structure:wherein each of R1 and R2 is H or 2H and a co-crystal former selected from adipic acid, citric acid, fumaric acid, maleic acid, succinic acid, or benzoic acid. Also within the scope of this invention are methods of making and using the same.
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