Compositions for treating pollinosis, allergic nephritis, atopic dermatitis, asthma or urticaria and health foods or functional foods which contain two crude drugs of pumpkin seeds and safflower together with at least one crude drug selected from among Plantago asiatica L., Louicera japonica Thunberg, Glycyrrhizae Radix, Coix lacryma-jobi Linne var. ma-yuen, Zingiberis Rhizoma, Turmeric, Zedoary and Artemisiae Argyi Forium as the active ingredients.