Disclosed herein is a synthetic peptide, which has an amino acid sequence that has 20-39 amino acid residues. The synthetic peptide has at least 80% amino acid sequence identity to SEQ ID NO: 1, and includes at least 20 consecutive residues that has at least 90% amino acid sequence identity to residues 11-30 of SEQ ID NO: 1. Also disclosed herein are pharmaceutical compositions containing the synthetic peptide and applications thereof. According to various embodiments of the present disclosure, the synthetic peptide is useful in promoting muscle or tendon regeneration, and/or arteriogenesis in a subject.本說明書揭示一種合成胜肽,其具有20-39個胺基酸殘基,且其序列與序列編號:1所示之胺基酸序列具有至少80%的胺基酸序列相似度。此合成胜肽有至少20個連續胺基酸殘基,其與序列編號:1所示之第11-30個胺基酸殘基具有至少90%的胺基酸序列相似度。本說明書揭示含有此合成胜肽的藥學組合物及其用途。根據本說明書所載的多種實施方式,此合成胜肽可用以促進肌肉或肌腱再生或促進動脈血管生成。