The present invention is excellent in masking effect for reducing unpleasant taste caused by acidic drugs, and further, compression molding capable of stably maintaining a good feeling of taking without decreasing the masking effect of unpleasant taste over time It is an object to provide a preparation. The compression-molded preparation of the present invention that has solved the problem contains coated particles obtained by coating an enteric polymer film on core particles containing an acidic drug, a gastric soluble polymer, a water-insoluble polymer, and a water-soluble polymer. It is characterized by that.本発明は、酸性薬物に起因する不快な味を低減させるマスキング効果に優れ、さらに、経時的に不快な味のマスキング効果が低下することなく、良好な服用感を安定して維持し得る圧縮成型製剤を提供することを課題とする。当該課題を解決した本発明の圧縮成型製剤は、酸性薬物、胃溶性高分子、水不溶性高分子及び水溶性高分子を含有する核粒子に腸溶性高分子の皮膜を施した被覆粒子を含有することを特徴とする。
