OPTIMIZED VARIANTS OF ANTI VEGF ANTIBODIES

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专利权人:

发明人:

KOENIG PATRICK,LEE CHINGWEI VIVIAN,RAJAGOPAL KARTHIKAN,FAMILI AMIN,FUH GERMAINE

申请号：

IN201817011396

公开号：

IN201817011396A

申请日:

2018.03.27

申请国别(地区):

IN

年份:

2018

代理人:

摘要：

The present invention provides anti VEGF antibodies and compositions that include anti VEGF antibodies (e.g. antibody conjugates fusion proteins and polymeric formuiations) and uses thereof for example for treatment of disorders associated with pathological angiogenesis. The present invention also provides methods of identifying antibody variants with improved properties for example enhanced binding affinity stability pharmacokinetics and/or expression.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/