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ANTI HUMAN VEGF ANTIBODIES WITH UNUSUALLY STRONG BINDING AFINITY TO HUMAN VEGF A AND CROSS REACTIVITY TO HUMAN VEGF B
专利权人:
发明人:
BALDI ALBERTO
申请号:
IN201617041038
公开号:
IN201617041038A
申请日:
2016.12.01
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Murine and humanized anti human VEGF antibodies and uses are disclosed. The anti human VEGF antibodies of the invention have higher binding affinity for human VEGF A are stronger inhibitors of the VEGF A induced proliferation of endothelial cells in culture as compared with anti human VEGF antibodies in the art. Moreover these antibodies cross react with human VEGF B. The antibodies of the invention inhibit tumor growth in vivo in greater extent than Bevacizumab (AvastinTM) when administered at the same dosage
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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