Patrick KOENIG,Chingwei Vivian LEE,Karthikan RAJAGOPAL,Amin FAMILI,Germaine FUH
申请号：
US15274612
公开号：
US20170096479A1
申请日:
2016.09.23
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention provides anti-VEGF antibodies and compositions that include anti-VEGF antibodies (e.g., antibody conjugates, fusion proteins, and polymeric formulations), and uses thereof, for example for treatment of disorders associated with pathological angiogenesis. The present invention also provides methods of identifying antibody variants with improved properties, for example, enhanced binding affinity, stability, pharmacokinetics, and/or expression.
