The variant of the optimization of anti-VEGF antibodies

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专利权人:

GENENTECH INC.

发明人:

KOENIG, Patrick,LEE, Chingwei Vivian,RAJAGOPAL, Karthikan,FAMILI, Amin,FUH, Germaine

申请号：

CO2018003863

公开号：

CO2018003863A2

申请日:

2018.04.11

申请国别(地区):

CO

年份:

2018

代理人:

摘要：

The present invention provides anti-VEGF antibody and the composition (for example, antibody conjugates, fusion protein and polymer formulations) comprising anti-VEGF antibody and its application, for example, relevant illness occurs with pathologic vessels for treating.The present invention also provides differentiate with the improved method of the antibody variants of property (for example, binding affinity, stability, pharmacokinetics and/or expression of enhancing).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/