Heteroaryl compounds piridona and AZA piridona as inhibitors of BTK activity

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专利权人:

F. HOFFMAN-LA ROCHE AG

发明人:

CRAWFORD, JAMES JOHN,ORTWINE, DANIEL FRED,WEI, BINQING,YOUNG, WENDY B

申请号：

CR20140194

公开号：

CR20140194A

申请日:

2014.04.28

申请国别(地区):

CR

年份:

2014

代理人:

摘要：

The heteromorphic pyridan and aza piridona compounds of equation 1 are provided, wherein one or two compounds of x1, X2 and X3 are n, including stereoisomers, tauqianros, and pharmaceutically acceptable salts that can be used to inhibit Btk quintasa； andSe proporcionan compuestos de heteroaril piridona y aza-piridona de Fórmula I, donde uno o dos de X1, X2, y X3 son N, e incluyendo estereoisómeros, tautómeros, y sales farmacéuticamente aceptables de los mismos, útiles para inhibir la quinasa Btk, y para

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