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Hydroxyl KRN7000 analogs and uses thereof
专利权人:
国立研究開発法人理化学研究所
发明人:
汐崎 正生,田代 卓哉,森 謙治,重浦 智邦,渡会 浩志,谷口 克
申请号:
JP2014528245
公开号:
JP6233890B2
申请日:
2013.08.02
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
The present invention aims to provide a novel KRN7000 analog biased to the Th2 type, which is expected to show an immunosuppressive effect, and a medicament containing same. A compound represented by the formula (I) wherein R 1 is a hydrogen atom or a hydroxyl group; two R 2 are the same or different and each is a hydrogen atom or a hydroxyl group; R 3 is a hydrocarbon group having 8-14 carbon atoms, which optionally has substituent(s); and R 4 is a hydrocarbon group having 18-24 carbon atoms, which optionally has substituent(s), or a salt thereof.
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