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DPP-IV resistant GIP hybrid polypeptides with selectable properties
专利权人:
Odile Esther Levy
发明人:
Odile Esther Levy,Alain D. Baron,Lawrence J. DSouza,Mary Erickson,Soumitra S. Ghosh,Michael R. Hanley,Samuel Janssen,Carolyn M. Jodka,Diana Y. Lewis,Christine M. Mack,David G. Parkes,Richard A. Pittne
申请号:
US12377856
公开号:
US08497240B2
申请日:
2007.08.17
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.
来源网站:
中国工程科技知识中心
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