Qian-Sheng Yu;Edward J. Goetzl;Nigel H. Greig;Weiming Luo;Harold W. Holloway;David Tweedie
发明人:
Nigel H. Greig,Weiming Luo,David Tweedie,Harold W. Holloway,Qian-Sheng Yu,Edward J. Goetzl
申请号:
US13310242
公开号:
US08927725B2
申请日:
2011.12.02
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of:wherein A, B and D are each oxygen or sulfur, provided that least one of A, B and D is sulfur; and R1-R8 are each independently hydrogen, hydroxyl, acyl, substituted acyl, acyloxy, substituted acyloxy, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, aryl, substituted aryl, amino, substituted amino, halogen, heterocycloalkyl, substituted heterocycloalkyl, heteroaryl, substituted heteroaryl, or a thio-containing group.