The United States of America; as represented by the Secretary; Department of Health and Human Services
发明人:
Nigel H. Grieg,Weiming Luo,David Tweedie,Harold W. Holloway,Qian-Sheng Yu,Edward J. Goetzl
申请号:
US14571138
公开号:
US09084783B2
申请日:
2014.12.15
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A compound, or a pharmaceutically acceptable salt or ester thereof, having a structure of:wherein A, B and D are each oxygen or sulfur, provided that least one of A, B and D is sulfur; and R1-R8 are each independently hydrogen, hydroxyl, acyl, substituted acyl, acyloxy, substituted acyloxy, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, alkoxy, substituted alkoxy, aryl, substituted aryl, amino, substituted amino, halogen, heterocycloalkyl, substituted heterocycloalkyl, heteroaryl, substituted heteroaryl, or a thio-containing group.