1. A device for delivering a bioactive agent through the dermal barrier, comprising: a microneedle and a plurality of nanostructures made on its surface, arranged in a predetermined pattern； a fluid-communicating composition with a microneedle containing a bioactive agent and having a viscosity of more than about 5 centipoise, for example, from about 10 centipoise to about 50 centipoise. 2. The device according to claim 1, characterized in that the concentration of the bioactive agent in the composition exceeds about 5 mg / ml, for example, from about 35 mg / ml to about 500 mg / ml. The device according to claim 1 or 2, in which the molecular weight of the bioactive agent exceeds about 100 kDa. A device according to claim 1, wherein the bioactive agent is a protein therapeutic agent. The device according to claim 1, wherein the composition further comprises one or more pharmaceutically acceptable excipients, for example, a pharmaceutically acceptable excipient selected from the group consisting of a solvent, a penetrating agent, a thickening agent, a wetting agent, a lubricant and a softener. The device according to claim 1, wherein the pattern further includes microstructures, wherein the cross-sectional size of the nanostructures is smaller than the cross-sectional size of the microstructures. The apparatus of claim 6, wherein the cross-sectional size of the microstructures is greater than about 500 nm, and the cross-sectional size of the nanostructures is less than about 300 nm. The device according to claim 6 or 7, further comprising second nanostructures whose cross-sectional size is smaller than the cross-sectional size of the microstructures and larger than the cross-sectional size of the first nanostructures. The device1. Устройство для доставки биоактивного агента через дермальный барьер, содержащее:микроиглу и множество изготовленных на ее поверхности наноструктур, скомпонованных в заданный паттерн；сообщающаяся по текучей среде с микроиглой композиция, со
