A medical delivery system wherein one of a container and a dosing assembly comprises a first fastening means (116) and the other one of the container and the dosing assembly comprises a second fastening means (114) and wherein the second fastening means is adapted to move at least a part of the first fastening means in a radial direction upon rotation of the container in a first rotational direction relative to the dosing assembly, whereby the first and second fastening means engage such that the container and the dosing assembly are locked for relative translational movement. A container and a dosing assembly for use in the medical delivery system.